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The full effect is observed only after some weeks of therapy. Maximal single dose must not exceed 150 milligram. Adults use two dosages at intervals not less than eight hours. Patients, for whom 150 milligram daily is inadequate, may experience improvement with increasing amount up to maximum 300 milligram daily.
Patients with liver pathology use the medicament with caution. Individuals with hepatic cirrhosis should take this medicine extremely carefully.
Contra indications and some special directives Wellbutrin is contra-indicated in people with hypersensitivity, history of seizures, psychogenic anorexia or bulimia, including history, concurrent use of inhibitors MAO. As elderly patients are characterized by the reduced function of kidney, it is advised to decreased dose.
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